Radical Stress Is More Cytotoxic in the Nucleus than in Other Organelles

PI3K and mTOR inhibitor, NVP-BEZ235, is more toxic than X-rays in prostate cancer cells

Background: Radiotherapy and adjuvant androgen deprivation therapy have historically been the first treatment choices for prostate cancer but treatment resistance often limits the capacity to effectively manage the disease. Therefore, alternative therapeutic approaches are needed. Here, the efficacies of radiotherapy and targeting the pro-survival cell signaling components epidermal growth fact...

Benzyl adenine is more effective than potassium silicate on decreasing the detrimental effects of heat stress in pepper (Capsicum annum cv. PS301)

ABSTRACT- Heat stress causes flower and fruit abscission in pepper. This study was conducted in the greenhouses of Isfahan University of Technology to evaluate the effect of foliar application of Benzyl adenine (BA) and potassium silicate (K2SiO3) under heat stress condition on bell pepper. Two factorial experiments based on completely randomized design with four concentrations of BA (0, 0.06, ...

Is amlodipine more cardioprotective than other antihypertensive drug classes?

Copyright © 2014 The Korean Association of Internal Medicine This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/ by-nc/3.0/) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited. pISSN 1226-3303 eISSN 2005-664...

Is Apis mellifera more sensitive to insecticides than other insects?

BACKGROUND Honey bees (Apis mellifera L.) are among the most important pollinators in natural and agricultural settings. They commonly encounter insecticides, and the effects of insecticides on honey bees have been frequently noted. It has been suggested that honey bees may be (as a species) uniquely sensitive to insecticides, although no comparative toxicology study has been undertaken to exam...

Is cognitive–behavioral therapy more effective than other therapies?